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The use of low doses of SSRIs in addition to clozapine and risperidone seems to help some individuals. There is no clear relationship to dose of clozapine or risperidone, though the obsessive compulsive symptoms are transient in some cases and may not require additional treatment. This effect seems to emerge earlier in the case of risperi- Managing Side Effects of Antipsychotic Drugs 29 done (weeks) than that of clozapine (months). In a preliminary study, olanzapine did not appear to increase the frequency of obsessive-compulsive symptoms in schizophrenia (21).

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